KNOWLEDGE HUB

Product of Conception: Comprehensive Molecular Chromosome Screening

Chromosomal causes of miscarriages Chromosomal aneuploidies (abnormal number of chromosomes) are the most common cause of first trimester miscarriage, accounting for more than 50% of spontaneous abortions1.  Aneuploidies observed in products of conception (POCs)...

PathCare Namibia AMR Data 2016 – 2021

Local, aggregated antimicrobial resistance data is valuable to guide empiric treatment strategies and to track epidemiological changes in susceptibility patterns over time. The data shown are determined from isolates identified in Pathcare Namibia microbiology...

Primary Aldosteronism: An Under-Recognised Problem

Primary aldosteronism (PA), also known as Conn’s syndrome, is common and has a significantly higher cardiovascular risk profile than sex-, age-, and BP-matched patients with essential hypertension.  PA is now considered a major public health issue, which requires a...

Covid-19 associated pulmonary aspergillosis (CAPA)

Covid-19 and ARDS In individuals with co-morbidities, defective immune responses to SARS-CoV-2 may allow unrestricted viral replication which elicits hyperinflammation and severe complications such as acute respiratory distress syndrome (ARDS). COVID-19 resulting in...

“Indeterminate” SARS-CoV-2 PCR results: interpretation and clinical guidance

This document is a supplement to the recent Pathcare clinical guidance document entitled “THE INTERPRETATION OF SARS-COV -2 RT-PCR CT VALUES IN CLINICAL PRACTICE” Background The polymerase chain reaction (PCR) test for the detection of SARS-CoV-2 in respiratory...

POLYMYXIN GUIDELINES

International Consensus Guidelines for the Optimal Use of the Polymyxins Due to a rapid increase in serious infections related to especially carbapenem producing Enterobacterales, the clinical use of the polymyxin antibiotics colistin (polymyxin E), and polymyxin B...

HYPERURICAEMIA AND GOUT: IMPORTANT LESSONS TO BE LEARNT

Introduction Gout is a common clinical disease and, furthermore, it is readily treatable and managed by the long-term use  of urate lowering medication. Gout, the clinical syndrome, needs to be distinguished from hyperuricaemia which refers to the increased...

Recent articles

PathCare Namibia AMR Data 2016 – 2021

Local, aggregated antimicrobial resistance data is valuable to guide empiric treatment strategies and to track epidemiological changes in susceptibility patterns over time. The data shown are determined from isolates identified in Pathcare Namibia microbiology...

Primary Aldosteronism: An Under-Recognised Problem

Primary aldosteronism (PA), also known as Conn’s syndrome, is common and has a significantly higher cardiovascular risk profile than sex-, age-, and BP-matched patients with essential hypertension.  PA is now considered a major public health issue, which requires a...

Covid-19 associated pulmonary aspergillosis (CAPA)

Covid-19 and ARDS In individuals with co-morbidities, defective immune responses to SARS-CoV-2 may allow unrestricted viral replication which elicits hyperinflammation and severe complications such as acute respiratory distress syndrome (ARDS). COVID-19 resulting in...

PathCare Namibia AMR Data 2016 – 2021

PathCare Namibia AMR Data 2016 – 2021

Local, aggregated antimicrobial resistance data is valuable to guide empiric treatment strategies and to track epidemiological changes in susceptibility patterns over time. The data shown are determined from isolates identified in Pathcare Namibia microbiology...

Primary Aldosteronism: An Under-Recognised Problem

Primary Aldosteronism: An Under-Recognised Problem

Primary aldosteronism (PA), also known as Conn’s syndrome, is common and has a significantly higher cardiovascular risk profile than sex-, age-, and BP-matched patients with essential hypertension.  PA is now considered a major public health issue, which requires a...

Covid-19 associated pulmonary aspergillosis (CAPA)

Covid-19 associated pulmonary aspergillosis (CAPA)

Covid-19 and ARDS In individuals with co-morbidities, defective immune responses to SARS-CoV-2 may allow unrestricted viral replication which elicits hyperinflammation and severe complications such as acute respiratory distress syndrome (ARDS). COVID-19 resulting in...

POLYMYXIN GUIDELINES

POLYMYXIN GUIDELINES

International Consensus Guidelines for the Optimal Use of the Polymyxins Due to a rapid increase in serious infections related to especially carbapenem producing Enterobacterales, the clinical use of the polymyxin antibiotics colistin (polymyxin E), and polymyxin B...

HYPERURICAEMIA AND GOUT: IMPORTANT LESSONS TO BE LEARNT

HYPERURICAEMIA AND GOUT: IMPORTANT LESSONS TO BE LEARNT

Introduction Gout is a common clinical disease and, furthermore, it is readily treatable and managed by the long-term use  of urate lowering medication. Gout, the clinical syndrome, needs to be distinguished from hyperuricaemia which refers to the increased...